Chemical compounds

A method for the treatment of HPV infection, genital warts, or cervical dysplasia comprising the administration of a compound of formula (I):

• wherein:
• n is 0, 1, or 2;
• R is hydrogen or alkyl;
• X is NR2, O;
• each R1 is the same or different and is independently selected from the group consisting of hydrogen, halogen, haloalkyl, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, —R10cycloalkyl, Ay, —NHR10Ay, Het, —NHHet, —NHR10Het, —OR2, —OAy, —OHet, —R10OR2, —NR2R3, —NR2Ay, —R10NR2R3, —R10NR2Ay, —R10C(O)R2, —C(O)R2, —CO2R2, —R10CO2R2, —C(O)NR2R3, —C(O)Ay, —C(O)NR2Ay, —C(O)Het, —C(O)NHR10Het, —R10C(O)NR2R3, —C(S)NR2R3, —R10C(S)NR2R3, —R10NHC(NH)NR2R3, —C(NH)NR2R3, —R10C(NH)NR2R3, —S(O)2NR2R3, —S(O)2NR2 Ay, —R10SO2NHCOR2, —R10SO2NR2R3, —R10SO2R2, —S(O)mR2, cyano, nitro, or azido;
• Y is optionally substituted alkylene, optionally substituted cycloalkylene, optionally substituted alkenylene, optionally substituted cycloalkenylene, or optionally substituted alkynylene;
• d is 0 or 1;
• Z is —R2, —OR2, —C(O)R2, —C(O)2R2, —S(O)mR2, —C(O)NR2R3, -Het, or -Ay, provided when d is 0, then Z is not -Het or -Ay;
• each m independently is 0, 1 or 2;
• each R10 is the same or different and is independently selected from alkylene, cycloalkylene, alkenylene, cycloalkenylene, and alkynylene;
• p is selected from 0, 1, 2, 3, or 4;
• each of R2 and R3 are the same or different and are independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, —R10cycloalkyl, —R10OH, —R10(OR10)w, and —R10NR5R6;
• w is 1-10;
• each of R5 and R6 are the same or different and are independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, and alkynyl;
• Ay represents an optionally substituted aryl group;
• Het represents an optionally substituted 5- or 6-membered heterocyclyl or heteroaryl group;
• or a pharmaceutically acceptable salt thereof to a human in need thereof.