Benzazepine derivatives and uses thereof

A compound of the formula I:

• wherein:
• Ar is optionally substituted indolyl;
• R1 is:
• hydrogen;
• or
• C1-6alkyl;
• and
• R2 is:
• hydrogen;
• C1-6alkyl;
• C1-6alkoxy;
• halo;
• halo-C1-6alkyl;
• hetero-C1-6alkyl;
• C1-6alkylsulfonyl;
• cyano;
• amino;
• C1-6alkylamino;
• di-C1-6alkylamino;
• heterocyclyl selected from piperazinyl, piperidinyl, pyrrolidinyl, morpholinyl, thiomorpholinyl, tetrahydropyranyl and tetrahydrofuranyl, each optionally substituted;
• heterocyclyl-C1-6alkyl selected from piperazinyl-C1-6alkyl, piperidinyl-C1-6alkyl, pyrrolidinyl-C1-6alkyl, morpholinyl-C1-6alkyl, thiomorpholinyl-C1-6alkyl, tetrahydropyranyl-C1-6alkyl and tetrahydrofuranyl-C1-6alkyl, the heterocyclyl portion of each optionally substituted;
• —(CH2)m—C(O)—NRaRb;
• —(CH2)m—SO2—NRaRb;
• —(CH2)m—(O)—ORc;
• —NRd—C(O)—Re;
• —NRd—SO2—Re;
• —O—C(O)—Re;
• —O—C(O)—NRaRb;
• —NRd—C(O)—NRaRb;
• or
• —NRd—C(O)—ORc;
• wherein m is 0 or 1 and Ra, Rb, Rc, Rd and Re each independently is hydrogen or C1-6alkyl.