US 7,622,142 B2 · Methods for treating glioblastoma with herbal compositions

Abstract

The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1α, interleukin-1β, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.

Claims28

Dependent claims

A method for increasing gene expression, to induce cellular apoptosis in a target glioblastoma cell of a subject in need thereof, of one or more genes selected from the group consisting of:

interleukin-1α, interleukin-1β, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein 1A, heat shock 70 kDa protein 1B, heat shock 70 kDa protein 6, and combinations thereof, comprising administering an effective amount of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger;
and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.

Dependencies are inferred from the claim text.

Methods for treating glioblastoma with herbal compositions

Life of this patent

Methods for treating glioblastoma with herbal compositions

Life of this patent

Abstract

Claims28