Dosage forms contained within a capsule or sachet
AssigneeAccu-Break Technologies, Inc.
InventorsLawrence Solomon, Allan S. Kaplan
Life of this patent
Estimating the term…
Abstract
Provided are pharmaceutical dosage forms within structures such as hollow capsules, gelcaps, or sachets, adapted to allow ingestion of a whole dose or a preferably predetermined fraction of said dose when desired.
Claims8
A dosage form comprising a capsule or sachet containing a divisible dose tablet, said tablet comprising a plurality of compressed segments, said tablet having a top and a bottom, and having a height that exceeds the width of said tablet, said height being measured vertically from the top to the bottom of said tablet while it is in a tablet die in which it is fully compressed, after said compression has been completed;
- and said width being measured as the greatest horizontal dimension of the tablet at a location halfway between said top and said bottom of said tablet, except that when the horizontal cross-section of said tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of said horizontal cross-section, and measuring the length of a line that is at right angle to said shorter sides, said segments being compressed in a tablet die to form a taller-than-wide segmented tablet in said tablet die, wherein at least two segments are active segments comprising a composition containing one or more active pharmaceutical ingredient, and at least one of said plurality of compressed segments is an inactive segment located between said at least two active segments, said inactive segment forming a breaking region for dividing said tablet there through to provide at least two tablettes each comprising a compressed active segment and a portion of the compressed inactive segment.
A dosage form comprising a capsule or sachet containing a divisible dose compressed tablet having first and second active compressed segments comprising a composition containing a drug or combination of drugs, and a third inactive compressed segment between said active segments wherein said active segments are:
- formulated to have immediate-release characteristics,
- pharmaceutically compatible with one another, or
- substantially indentical compositions;
- said compressed tablet having a top and a bottom, and having a height that exceeds the width of said tablet, said height being measured vertically from the top to the bottom of said tablet while it is in a tablet die in which it is fully compressed, after said compression has been completed;
- and said width being measured as the greatest horizontal dimension of the tablet at a location halfway between said top and said bottom of said tablet, except that when the horizontal cross-section of said tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of said horizontal cross-section, and measuring the length of a line that is at right angle to said shorter sides, said segments being compressed in a tablet die to form a taller-than-wide segmented tablet in said tablet die, wherein said third inactive segment forming a breaking region for dividing said tablet there through to provide at least two tablettes each comprising a compressed active segment and a portion of the compressed inactive segment.
Dependencies are inferred from the claim text.