Nano-structured polymers for use as implants
AssigneePurdue Research Foundation
InventorsKaren M. Haberstroh, Thomas J. Webster, Anil Thapa, Derick C. Miller
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Abstract
Polymeric materials and processes for making the same are provided herein wherein said polymeric materials have nano-sized topological features or textures. These features have dimensions in various ranges including, but not limited to, dimensions less than about 100 nanometers. In addition, polymeric materials are described herein that have a surface roughness of about 50 nm or greater. These polymeric materials are useful for making implants for soft tissues, such as bladder tissue replacement implants. Methods of treatment using such implants are also described. In such methods, polymers that are biocompatible, and biodegradable are also described.
Claims28
A nano-structured synthetic implant comprising a polymeric material, said polymeric material displaying nano-sized surface features and a surface roughness of 50 nm or greater, wherein said surface features comprise a dimension having a size within the range of 25 nm to less than 100 nm.
A nano-structured synthetic implant comprising a polymeric material, said polymeric material displaying nano-sized surface features and a surface roughness of 50 nm or greater, wherein the surface features are formed by chemical treatment of said polymeric material, and have one or more dimensions in the range from 50 nm to less than 100 nm.
A nano-structured synthetic implant, said implant consisting essentially of
- a polymeric material having a surface roughness of 50 nm to less than 100 nm and a further surface feature having a dimension in the range from 50 nm to less than 100 nm;
- and
- a population of cells.
A nano-structured synthetic implant comprising a polymeric material, said polymeric material comprising peaks and valleys formed on the surface of said polymeric material, wherein a dimension selected from the group consisting of peak height, valley depth, peak width at half height and valley width at half depth, is within the range of 25 nm to less than 100 nm.
Dependencies are inferred from the claim text.