Mycoplasma hyopneumoniae bacterin vaccine

A vaccine composition for immunizing a porcine animal against infection by Mycoplasma hyopneumoniae and an additional bacterial or viral pathogen which comprises

• an immunizing amount of an inactivated Mycoplasma hyopneumoniae bacterin;
• an immunizing amount of at least one bacterial or viral antigen selected from the group consisting of:
• Haemophilus parasuis, Pasteurella multocida, Streptococcus suis, Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Salmonella choleraesuis, Erysipelothrix rhusiopathiae, leptospira bacteria, swine influenza virus (SIV), porcine reproductive and respiratory syndrome virus (PRRSV), and porcine circovirus (PCV);
• an adjuvant mixture comprising an acrylic acid polymer and a mixture of a metabolizable oil and a polyoxyethylene-polyoxypropylene block copolymer;
• and
• a pharmaceutically acceptable carrier which vaccine composition after a single administration elicits protective immunity from Mycoplasma hyopneumoniae.

A vaccine composition for immunizing a porcine animal against infection by Mycoplasma hyopneumoniae and a viral pathogen which comprises

• an immunizing amount of an inactivated Mycoplasma hyopneumoniae bacterin;
• an immunizing amount of at least one viral antigen selected from the group consisting of:
• swine influenza virus (SIV), porcine reproductive and respiratory syndrome virus (PRRSV), and porcine circovirus (PCV);
• an adjuvant mixture comprising an acrylic acid polymer and a mixture of a metabolizable oil and a polyoxyethylene-polyoxypropylene block copolymer;
• and
• a pharmaceutically acceptable carrier which vaccine composition after a single administration elicits protective immunity from Mycoplasma hyopneumoniae.