Peptide originating from vaccinia virus
AssigneeMayo Foundation for Medical Education and Research
InventorsGregory A. Poland, Inna G. Ovsyannikova, David C. Muddiman, Kenneth L. Johnson
Life of this patent
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Abstract
A vaccine for preventing or treating Orthopoxvirus infection that induces a protective or therapeutic immune response, wherein the vaccine comprises (1) an amino acid sequence of 20 amino acid or less (preferably 12 amino acid or less and most preferably 11 amino acid or less) of the formula X1-SEQ ID NO:1-X2, wherein X1 and X2 are peptides of 0-11 amino acid in length comprising either native or non-native amino acid sequences, (2) an antigen-presenting cell pulsed with the peptide, or (3) a cell sensitized in vitro to the peptide is disclosed.
Claims7
An isolated peptide, wherein the peptide consists of X1-SEQ ID NO:1-X2, wherein X1 and X2 are amino acid segments of 0-11 amino acids in length.
Dependencies are inferred from the claim text.