3-deoxyglucosone and skin
AssigneeDynamis Therapeutics, Inc.
InventorsAnnette Tobia, Francis Kappler
Life of this patent
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Abstract
The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
Claims18
A method of inhibiting 3-Deoxyglucosone (3DG) synthesis in the skin of a mammal, said method comprising administering to a mammal in need thereof an effective amount of meglumine or a salt thereof to inhibit said 3DG synthesis, further wherein said meglumine or salt thereof is administered via a topical route in a pharmaceutical composition, selected from the group consisting of a lotion, a cream, a gel, a liniment, an ointment, a paste, a solution, a powder, and a suspension.
A method of treating skin aging in a mammal, said method comprising, administering to a mammal in need thereof an effective amount of meglumine or a salt thereof which inhibits at least one of the members of the group consisting of the production of said 3DG, the accumulation of said 3DG and the function of said 3DG in skin, further wherein said meglumine or salt thereof is administered via a topical route in a pharmaceutical composition selected from the group consisting of a lotion, a cream, a gel, a liniment, an ointment, a paste, a solution, a powder, and a suspension.
Dependencies are inferred from the claim text.