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US 7,622,110 B2Granted
Compositions and methods for the systemic treatment of arthritis
AssigneeBaylor Research Institute
InventorsJacques F. Banchereau, Maria Virginia Pascual
Life of this patent
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Abstract
The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.
Claims3
A method for treating a patient with systemic onset juvenile idiopathic arthritis (SOJIA) comprising:
- a) identifying a patient having symptoms of SOJIA;
- and
- b) administering to the patient a composition comprising a therapeutically effective amount to treat SOJIA of at least one active agent which reduces or blocks the interaction between interleukin-1β(IL-1β) and an IL-1 (IL-1) receptor wherein the active agent comprises an IL-1β antagonist protein which binds to IL-1β, whereby a patient with SOJIA is therefore treated.
Dependencies are inferred from the claim text.