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US 7,622,105 B2Granted
Modified cytokines for use in cancer therapy
AssigneeFondazione Centro San Raffaele Del Monte Tabor
InventorAngelo Corti
Life of this patent
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Abstract
Cytokine derivatives capable of homing the tumoral vessels and the antigen presenting cells and the use thereof as antitumoral agents.
Claims11
A method of treating or diagnosing a cancer patient comprising administering simultaneously, sequentially or separately:
- (a) an effective amount of a conjugation product of TNF and a ligand of the CD13 receptor, wherein the ligand is a peptide comprising the NGR motif, and (b) an effective amount of IFNγ.
Dependencies are inferred from the claim text.