Sheath-mounted arterial plug delivery device

A method of facilitating hemostasis of a blood vessel puncture, the method comprising:

• inserting a tubular device into a puncture in a blood vessel to establish access to the blood vessel;
• providing a vessel closure system around the tubular device;
• providing a proximal stop having a distal end adapted to be disposed within a space between the vessel closure system and the tubular device, the proximal stop defining a single chamber aperture sized to receive the tubular device;
• introducing a hemostasis promoting material into the space between the tubular device and vessel closure system, the hemostasis promoting material being situated distal to a distal end of the proximal stop;
• withdrawing the tubular device completely from the vessel closure system;
• inserting a pusher into the vessel closure system after the tubular device is withdrawn, the pusher being separate from the proximal stop and including a distal end sized for insertion into the single chamber aperture of the proximal stop;
• and
• effecting proximal movement of the vessel closure system with respect to the pusher to deliver the hemostasis material adjacent to the puncture and facilitate hemostasis of the puncture.