Method and apparatus to deliver drug and pacing therapy for treatment of cardiac disorders
AssigneeCardiac Pacemakers, Inc.
InventorsJoseph M. Pastore, Jeffrey Ross
Life of this patent
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Abstract
A drug delivery system uses an electrically sensitive polymer to store a drug and applies an electric field onto the electrically sensitive polymer for quantitatively and temporally controlled drug delivery. In one embodiment, the drug delivery system is part of a cardiac rhythm management (CRM) system that includes an implantable CRM device and an implantable drug delivery device. The implantable CRM device delivers electrical therapies to a heart and controls the implantable drug delivery device by producing the electrical field with controllable amplitude, frequency, and timing.
Claims19
A system, comprising:
- an implantable drug delivery device including:
- a drug storage device including a polymeric matrix made of an electrically sensitive polymer having a structure that is electrically controllable by applying an electric field on the electrically sensitive polymer, the structure including an electrically controllable porosity or an electrically controllable binding affinity;
- a drug embedded in the polymeric matrix;
- and
- a plurality of electrodes, coupled to the drug storage device, the plurality of electrodes to apply a plurality of electric fields each on a portion of the electrically sensitive polymer and having an individually controllable amplitude;
- and
- an implantable lead including a proximal end including a lead connector providing for a detachable connection to an implantable cardiac rhythm management (CRM) device and a distal end at the implantable drug delivery device, the implantable lead providing for electrical connections between the implantable CRM device and the plurality of electrodes to allow a plurality of drug delivery signals controlling the application of the plurality of electric fields to be delivered from the implantable CRM device to the plurality of electrodes.
Dependencies are inferred from the claim text.