Method and system to synchronize acoustic therapy with ultrasound imaging

A method for synchronizing non-imaging ultrasound waves and ultrasound imaging waves, so that interference in an ultrasound image due to the non-imaging ultrasound waves is limited to only a portion of the ultrasound image, comprising the steps of:

• (a) using a transducer that generates non-imaging ultrasound waves to detect scattered ultrasound imaging waves, the transducer that generates non-imaging ultrasound waves producing an output signal that is indicative of the ultrasound imaging waves that are detected;
• (b) manipulating the output signal to generate a synchronization signal;
• and
• (c) using the synchronization signal to selectively control generation of the non-imaging ultrasound waves by the transducer that generates non-imaging ultrasound waves, such that interference in the ultrasound image generated using the ultrasound imaging waves due to the non-imaging ultrasound waves is limited to only a portion of the ultrasound image.

A method for using ultrasound to simultaneously image a target area and apply therapeutic ultrasound waves to a treatment site disposed within said target area, comprising the steps of:

• (a) using an ultrasound imaging system to generate an ultrasound image of the target area;
• (b) without using the ultrasound imaging system, detecting the scattered ultrasound imaging waves generated by the ultrasound imaging system, producing an output signal that is indicative of the ultrasound imaging waves;
• (c) manipulating the output signal to generate a synchronization signal;
• and
• (d) using the synchronization signal to selectively control a transducer that generates the therapeutic ultrasound waves, such that:
• (i) the synchronization signal ensures that at least a portion of the ultrasound image is free from interference due to the therapeutic ultrasound waves;
• and
• (ii) a focal point of the therapeutic ultrasound transducer is able to be visualized in the ultrasound image generated by the ultrasound imaging system without being obscured by interference caused by the therapeutic ultrasound waves as they induce a therapeutic effect at the treatment site.

A system for enabling non-imaging ultrasound to be applied to a target area while simultaneously imaging the target area with an ultrasound imaging system, to enable real-time ultrasound imaging of the target area to be achieved while applying non-imaging ultrasound to the target area, comprising:

• (a) a receiver configured to detect scattered ultrasound imaging waves generated by an ultrasound imaging transducer included within the ultrasound imaging system, independently of the ultrasound imaging system, producing an output signal that is indicative of the ultrasound imaging waves;
• and
• (b) a synchronization processor logically coupled to the receiver, the synchronization processor being configured to generate a synchronization signal to be used to control a transducer employed for producing non-imaging ultrasound waves, so that at least a portion of an ultrasound image generated using the ultrasound imaging transducer does not include interference due to the non-imaging ultrasound waves;
• wherein the receiver comprises the transducer that generates the non-imaging ultrasound waves.

A synchronization processor configured to enable non-imaging ultrasound waves to be applied to a target area while imaging the target area with an ultrasound imaging system, and to prevent a real-time ultrasound image of the target area from being obscured due to interference caused by the non-imaging ultrasound waves, comprising:

• (a) an input configured to be coupled to an output signal from a receiver that is independent of the ultrasound imaging system, but which is configured to detect scattered ultrasound imaging waves generated by an ultrasound imaging transducer that is included within the ultrasound imaging system, the receiver producing the output signal, which is indicative of the ultrasound imaging waves;
• and
• (b) an output configured to be coupled to control activation of a non-imaging transducer, so that the non-imaging transducer is synchronized to produce non-imaging ultrasound waves in regard to production of the ultrasound imaging waves by the ultrasound imaging transducer, so that at least a portion of an ultrasound image generated using the ultrasound imaging transducer does not include interference due to the non-imaging ultrasound waves produced by the non-imaging transducer;
• and wherein the synchronization processor is configured to implement the following functions:
• (a) amplifying the output signal, producing an amplified output signal;
• (b) averaging a plurality of amplitudes of the amplified output signal to generate an averaged output signal;
• (c) amplifying the averaged output signal to produce an amplified averaged output signal;
• (d) clamping the amplified averaged output signal to insure that the amplified averaged output signal does not exceed a maximum value, thereby generating a clamped signal;
• and
• (e) using the clamped signal to generate a pulsed signal at the output of the synchronization processor, for triggering the con imaging transducer to produce non-imaging ultrasound waves.

A therapeutic ultrasound system configured for automatic synchronization with an ultrasound imaging system, to enable real-time ultrasound imaging of a target area to be achieved while applying therapeutic ultrasound to the target area, comprising:

• (a) a therapeutic transducer configured to produce therapeutic ultrasound waves;
• (b) a receiver configured to detect scattered ultrasound imaging waves generated by an ultrasound imaging transducer included within the ultrasound imaging system, the receiver producing an output signal that is indicative of the ultrasound imaging waves independently of the ultrasound imaging system;
• and
• (c) a synchronization processor logically coupled to the receiver, the synchronization processor being configured to generate a synchronization signal used to control activation of the therapeutic transducer in response to the output signal, so that the therapeutic transducer is synchronized in producing the therapeutic ultrasound waves in regard to activation of the ultrasound imaging transducer, and so that at least a portion of an ultrasound image generated with the ultrasound imaging transducer does not include interference due to therapeutic ultrasound waves produced by the therapeutic transducer.

A method for synchronizing non-imaging ultrasound waves and ultrasound imaging waves produced by an ultrasound imaging system, so at least a portion of an ultrasound image produced by the ultrasound imaging system is free from interference due to the non-imaging ultrasound waves, comprising the steps of:

• (a) providing an ultrasound imaging system including an ultrasound imaging transducer;
• (b) providing an ultrasound receiver that is not part of the ultrasound imaging system;
• (c) using the ultrasound receiver for receiving scattered ultrasound imaging waves that were produced by the ultrasound imaging transducer, producing an output signal in response thereto;
• (d) manipulating the output signal to generate a synchronization signal;
• and
• (e) using the synchronization signal to selectively control generation of the non-imaging ultrasound waves, such that at least a portion of the ultrasound image is free from interference due to the non-imaging ultrasound waves.

A therapeutic ultrasound system configured for automatic synchronization with an ultrasound imaging system that includes an ultrasound imaging transducer for producing ultrasound imaging waves, to enable real-time ultrasound imaging of a target area to be achieved while applying therapeutic ultrasound to the target area, comprising:

• (a) a therapeutic transducer configured to produce therapeutic ultrasound waves;
• (b) a receiver configured to detect scattered ultrasound imaging waves generated by the ultrasound imaging transducer included within the ultrasound imaging system, the receiver producing an output signal that is indicative of the ultrasound imaging waves detected, where the receiver is not part of the ultrasound imaging system;
• and
• (c) a synchronization processor logically coupled to receive the output signal from receiver, the synchronization processor being configured to generate a synchronization signal used to control activation of the therapeutic transducer in response to the output signal, so that the therapeutic transducer is synchronized in producing the therapeutic ultrasound waves in regard to activation of the ultrasound imaging transducer, and so that at least a portion of an ultrasound image generated with the ultrasound imaging transducer does not include interference due to therapeutic ultrasound waves produced by the therapeutic transducer.