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AssigneesVirginia Commonwealth University Intellectual Property Foundation, Organogenesis, Inc.
InventorsDavid G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran
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The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
Synthetic electrospun collagen fibers electrospun from a solvent comprising a halogenated alcohol comprising a repeated longitudinal banding pattern, wherein the repeated banding pattern occurs at a spacing of about 65 nm to about 67 nm;
A composition comprising electroprocessed collagen comprising a repeated longitudinal banding pattern, wherein the repeated banding pattern occurs at a spacing of about 65 nm to about 67 nm;
A composition comprising synthetic electroprocessed collagen in a matrix, the matrix comprising a pore size in a range of about 0.2 microns to about 2.3 microns;
A composition comprising electroprocessed collagen comprising a blend of at least two types of collagen;
Dependencies are inferred from the claim text.