# US 7,613,573 B2 · Pricing of the identification service by a registry which identifies prospective donors having particular bloodtypes to a requisitioner

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- Number: US 7,613,573 B2
- Document ID: US7613573B2
- Status: Granted
- Kind: B2
- Application number: 11/412,667
- Filed: 2006-04-27
- Published: 2006-09-14
- Granted: 2009-11-03
- Earliest claimed: 2006-04-27
- Assignees: Bio, Inc.
- Inventors: Yi Zhang; Michael Seul
- Web page: https://patentgrep.com/patent/US7613573B2

## CPC

- G16H 40/20: for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
- G06Q 30/02: Marketing; Price estimation or determination; Fundraising
- G06Q 30/0202: Market predictions or forecasting for commercial activities
- G16H 40/67: for remote operation
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G06Q: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR

## Abstract

Disclosed is a registry for candidate transfusion donors, which invokes an inventory management policy to create and actively manage lists of candidate donors in order to minimize imbalances between demand and supply across multiple regions and across multiple categories of donors and recipients. Together with a genotyping laboratory, the registry does targeted recruitment of prospective donors who are typed for a set of genetic markers relating to clinically relevant antigens including mutations of Human Erythrocyte Antigens (HEA), genetic variants of Rh, and possibly additional antigens such as HLA and HPA. The registry monitors incoming demand for transfusion antigen genotypes, preferably stratify the demand into a set of categories representing stable subpopulations, and will apply strategies, disclosed herein, to tune the composition of candidate donor lists to match the demand, thereby avoiding excess, and unnecessary, typing of candidate donors.

## Claims

### Claim 1

A method of pricing by a registry which identifies prospective donors having particular bloodtypes to a requisitioner seeking to recruit such donors for blood donation, comprising determining, using a processor: expenses relating to recruiting candidate donors and determining their bloodtype, the number of candidate donors analyzed being chosen to ensure fulfillment of a preset fraction of the anticipated requests received, on average, per period of operation; the length of time during which donations by a selected candidate donor are, or can be, collected by a requisitioner; and proceeds generated by the requisitioner from sale of products derived from blood donated by a selected candidate; and adjusting the price charged by the registry for said identification to reflect: said expenses relating to recruiting; said length of time; and the proceeds generated from said sale of said products and wherein said price charged is output in a user readable format.

### Claim 2 (depends on 1)

The method of claim 1 wherein the number of candidate donors are further selected such that the expenses relating to recruiting candidate donors to be analyzed do not exceed an upper limit.

### Claim 3 (depends on 1)

The method of claim 1 wherein the bloodtypes comprise multiple phenotypes correlating with expression of antigens on human erythrocytes.

### Claim 4 (depends on 3)

The method of claim 3 wherein the antigenic phenotypes are from major and minor blood group systems.

### Claim 5 (depends on 1)

The method of claim 1 wherein the bloodtypes include Duffy, Dombrock, Landsteiner-Wiener, Colton, Scianna, Diego, Kidd, Kell, Lutheran and MNS.

### Claim 6 (depends on 1)

The method of claim 1 wherein identifying candidate donors having a particular bloodtype comprises analysis of a designated set of genetic determinants for expression of antigenic markers defining the bloodtype.

### Claim 7 (depends on 6)

The method of claim 6 further including analyzing said designated set of genetic determinants concurrently.

### Claim 8 (depends on 7)

The method of claim 7 further including pricing blood products produced from donations by donors with desirable bloodtype such that the price of said blood products is independent of the number of matched determinants.

### Claim 9 (depends on 7)

The method of claim 7 wherein revenue from the sale of blood products produced from donations by donors with desirable bloodtype is independent of the number of matched determinants.