# US 7,613,513 B1 · System and method for determining cardiac geometry

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- Number: US 7,613,513 B1
- Document ID: US7613513B1
- Status: Granted
- Kind: B1
- Application number: 10/612,770
- Filed: 2003-07-01
- Granted: 2009-11-03
- Earliest claimed: 2003-07-01
- Assignees: Pacesetter, Inc.
- Inventors: James E. Brewer; Mark W. Kroll
- Web page: https://patentgrep.com/patent/US7613513B1

## CPC

- A61N 1/3627: {for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy}
- A61B 5/0295: using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
- A61B 5/1076: {for measuring dimensions inside body cavities, e.g. using catheters (A61B3/1005 takes precedence)}
- A61B 5/349: Detecting specific parameters of the electrocardiograph cycle
- A61N 1/36507: {controlled by gradient or slope of the heart potential}
- A61B 5/0816: {Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00)}
- A61B 5/11: Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb {(A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721)}
- A61B 5/145: Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value {; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue} (non-radiation detecting or locating of foreign bodies in blood A61B5/06)
- A61N 1/36521: {the parameter being derived from measurement of an electrical impedance}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An exemplary method includes delivering an electrical signal to a first position in or adjacent to a cardiac chamber; sensing a potential generated by the delivered electrical signal at a second position; and determining a parameter based, at least in part, on the sensing wherein the parameter relates to cardiac geometry. Other exemplary methods, devices and/or systems are also disclosed.

## Claims

### Claim 1

A method comprising:
delivering an electrical signal to a first position using at least a first electrode located in or adjacent to a first cardiac chamber;
sensing a potential generated by the delivered electrical signal using at least a second electrode located at a second position in or adjacent to a second cardiac chamber; and
determining a change in an inter-electrode spacing between the first electrode and the second electrode based, at least in part, on a percent change of the sensed potential relative to a baseline potential.

### Claim 2 (depends on 1)

The method of claim 1, wherein the delivering delivers the electrical signal using a unipolar configuration.

### Claim 3 (depends on 1)

The method of claim 1, wherein the first position is in a right ventricle or in a vessel.

### Claim 4 (depends on 1)

The method of claim 1, wherein the delivering delivers the electrical signal using a ring electrode.

### Claim 5 (depends on 1)

The method of claim 1, Wherein the second position is in a vessel.

### Claim 6 (depends on 1)

The method of claim 1, wherein the second position is in a cardiac chamber.

### Claim 7 (depends on 1)

The method of claim 1, wherein the sensing senses the potential using a unipolar configuration.

### Claim 8 (depends on 1)

The method of claim 1, wherein the sensing occurs during a refractory period.

### Claim 9 (depends on 1)

The method of claim 1, wherein the delivering occurs during a refractory period.

### Claim 10 (depends on 1)

The method of claim 1, further comprising determining a ventricular volume from the inter-electrode spacing between the first electrode and the second electrode.

### Claim 11 (depends on 1)

The method of claim 1, further comprising determining a ventricular distance from the change in the inter-electrode spacing between the first electrode and the second electrode.

### Claim 12 (depends on 1)

The method of claim 1, further comprising determining a left ventricular diameter from the change in the inter-electrode spacing between the first electrode and the second electrode.

### Claim 13 (depends on 1)

The method of claim 1, further comprising determining a stage of congestive heart failure.

### Claim 14 (depends on 1)

The method of claim 1, further comprising delivering cardiac therapy based, at least in part, on the sensing.

### Claim 15

An apparatus comprising:
means for delivering an electrical signal to a first position using at least a first electrode located in or adjacent to a first cardiac chamber;
means for sensing a potential generated by the delivered electrical signal at a second position using at least a second electrode located in or adjacent to a second cardiac chamber;
means for determining a percent change of the sensed potential relative to a baseline potential; and
means for determining a change in an inter-electrode spacing between the first electrode and the second electrode based, at least in part, on the percent change of the sensed potential.

### Claim 16 (depends on 15)

The apparatus of claim 15 wherein the means for delivering an electrical signal comprises a power source, a lead and an electrode.

### Claim 17 (depends on 15)

The apparatus of claim 15 wherein the mean for sensing a potential comprises an electrode, a lead and a circuit.

### Claim 18 (depends on 15)

The apparatus of claim 15 wherein the means for determining a change in an inter-electrode spacing comprises an implantable and programmable device.

### Claim 19

An implantable cardiac system comprising:
an implantable device having a case capable of acting as an electrode;
one or more implantable leads having one or more electrodes wherein the one or more leads are connectable to the device; and
circuitry that is operative to deliver an electrical signal to a first electrode position in or adjacent to a first cardiac chamber, sense a potential generated by the delivered electrical signal at a second electrode position in or adjacent to a second cardiac chamber, and
a controller adapted to determine a percent change of the sensed potential relative to a baseline potential and to determine a change in an inter-electrode spacing between the first electrode and the second electrode based, at least in part, on the percent change of the sensed potential.

### Claim 20 (depends on 19)

The system of claim 19 wherein the one or more implantable leads comprises at least two leads including a first lead that is configured for placement in a right ventricle and a second lead that is configured for placement in a left ventricle.

### Claim 21 (depends on 20)

The system of claim 20 wherein the circuitry is operative to deliver an electrical signal to a first electrode carried by the first lead, and to sense a potential generated by the delivered electrical signal at a second electrode carried by the second lead.

### Claim 22

A method comprising:
delivering an electrical signal to a first position using a first electrode located in or adjacent to a cardiac chamber using a unipolar electrode configuration;
sensing a potential generated by the delivered electrical signal using a second electrode located at a second position;
determining a percent change of the sensed potential relative to a baseline potential; and
determining a change in an inter-electrode spacing between the first electrode and the second electrode based, at least in part, on the percent change of the sensed potential.
