# US 7,613,512 B2 · Gradually synchronized simultaneous atrial and ventricular pacing for cardiac rhythm discrimination

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- Number: US 7,613,512 B2
- Document ID: US7613512B2
- Status: Granted
- Kind: B2
- Application number: 11/615,490
- Filed: 2006-12-22
- Published: 2008-06-26
- Granted: 2009-11-03
- Earliest claimed: 2006-12-22
- Assignees: Medtronic, Inc.
- Inventors: Troy E. Jackson; Mark L. Brown; Jeffrey M. Gillberg
- Web page: https://patentgrep.com/patent/US7613512B2

## CPC

- A61N 1/3622: {comprising two or more electrodes co-operating with different heart regions}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

A cardiac medical device used for delivering anti-tachycardia pacing in both the atrial and ventricular regions in a simultaneous manner, while preventing potential of inducing atrial arrhythmia. The pacing pulses may be synchronized in a gradual manner so that simultaneous delivery of the pulses is ultimately achieved at reduced risk of inducing atria arrhythmia. The pacing pulses may also be synchronized immediately after a determination is made whether simultaneous pacing purses will be delivered in the vulnerable regions of the cardiac cycle.

## Claims

### Claim 1

A cardiac medical device for delivering anti-tachycardia pacing, comprising:
circuitry for delivering cardiac pacing pulses;
an input signal processing circuit;
a plurality of electrodes operatively connected to the circuitry and to the input signal processing circuit and implantable within a patient; and
a controller electrically connected to the circuitry for delivering pacing pulses and to the input signal processing circuit, the controller detecting a tachycardia and controlling the circuitry to deliver a plurality of pacing pulses via the plurality of electrodes in response to detection of the tachycardia via the electrodes, the plurality of pacing pulses including atrial pacing pulses and ventricular pacing pulses, wherein one or more of the atrial pacing pulses is delivered out of phase with a corresponding one or more of the ventricular pacing pulses, and wherein the controller is configured to gradually shift a phase difference between the delivered atrial pacing pulses and the delivered ventricular pacing pulses over a predetermined number of pacing cycles until the pacing pulses are delivered in phase.

### Claim 2 (depends on 1)

The cardiac medical device of claim 1, wherein the gradual phase shift includes gradually shifting the timing of the atrial pacing pulses relative to the ventricular pacing pulse.

### Claim 3 (depends on 1)

The cardiac medical device of claim 1, wherein the gradual phase shift includes gradually shifting the timing of the ventricular pacing pulses relative to the atrial pacing pulses.

### Claim 4 (depends on 1)

The cardiac medical device of claim 1, wherein the gradual phase shift includes maintaining a pacing cycle timing of each ventricular pacing pulse generally constant.

### Claim 5 (depends on 1)

The cardiac medical device of claim 1, wherein the controller further delivers generally simultaneous pacing pulses to the atrium and the ventricle over several pacing cycles to provide anti-tachycardia pacing after the pacing pulses are gradually shifted in phase.

### Claim 6 (depends on 1)

The cardiac medical device of claim 1, wherein the controller measures a cycle length of the tachycardia, delivers the atrial pacing pulses at a cycle length that is a first predetermined percentage of the tachycardia cycle length, and delivers the ventricular pacing pulses at a cycle length that is a second predetermined percentage of the tachycardia cycle length.

### Claim 7 (depends on 6)

The cardiac medical device of claim 6, wherein the first predetermined percentage is greater than the second predetermined percentage.

### Claim 8 (depends on 6)

The cardiac medical device of claim 6, wherein the first predetermined percentages and the second predetermined percentage are less than 100 percent.

### Claim 9 (depends on 6)

The cardiac medical device of claim 6, wherein the first predetermined percentage and the second predetermined percentage are not equal.

### Claim 10 (depends on 1)

The cardiac medical device of claim 1, wherein the controller delivers the atrial pacing pulses at a constant cycle length at least until the atrial and ventricular pacing pulses are delivered in phase.

### Claim 11 (depends on 1)

The cardiac medical device of claim 1, wherein the controller delivers the atrial and ventricular pacing pulses at equal cycle lengths after the atrial and ventricular pacing pulses are delivered in phase.

### Claim 12 (depends on 1)

The cardiac medical device of claim 1, wherein the controller delivers the pacing pulses together in phase after a determination that simultaneous pacing pulses fall outside vulnerable regions of the cardiac cycle.

### Claim 13

A computer-readable medium programmed with instructions for delivering anti-tachycardia pacing, the medium comprising instructions for causing a programmable processor to:
monitor patient parameters in an atrium and a ventricle to detect a tachycardia;
deliver pacing pulses to the atrium and the ventricle each pacing cycle upon detection of the tachycardia, one or more initial atrial pacing pulses being delivered out of phase with corresponding one or more initial ventricular pacing pulses; and
gradually shift the phase difference between the pacing pulses delivered in the atrium and the ventricle over a quantity of pacing cycles until the pacing pulses are delivered together in phase each pacing cycle.

### Claim 14 (depends on 13)

The computer-readable medium of claim 13, wherein the atrial pacing pulses are delivered at an atrial cycle length and the ventricular pacing pulses are delivered at a ventricular cycle length, and the quantity of pacing cycles of the gradual shift being based on the atrial and ventricular cycle lengths.

### Claim 15 (depends on 13)

The computer-readable medium of claim 13, wherein the quantity of pacing cycles of the gradual shift of the phase difference is based on the phase difference of the initial atrial and ventricular pacing pulses.

### Claim 16 (depends on 13)

The computer-readable medium of claim 13, wherein the pacing pulses are delivered together in phase after a determination that simultaneous pacing pulses fall outside vulnerable regions of the cardiac cycle.

### Claim 17 (depends on 13)

The computer-readable medium of claim 13, wherein the tachycardia comprises one of a supraventricular tachycardia or a ventricular tachyarrhythmia.

### Claim 18

A method of providing simultaneous atrial and ventricular pacing, comprising:
monitoring patient parameters in an atrium and a ventricle;
detecting an abnormal or suspected abnormal heart rhythm in one of the atrium and the ventricle;
determining whether delivery of simultaneous atrial and ventricular pacing pulses falls within vulnerable regions of the cardiac cycle;
delivering pacing pulses to the atrium and the ventricle each pacing cycle, the atrial pulses being delivered out of phase with the corresponding ventricular pacing pulses if simultaneous delivery of such atrial and corresponding ventricular pacing pulses falls within vulnerable regions of the cardiac cycle;
gradually shifting any out of phase atrial and ventricular pacing pulses relative to each other over a quantity pacing cycles until the pacing pulses are delivered in phase each pacing cycle; and
delivering atrial and ventricular pacing pulses in phase.

### Claim 19 (depends on 18)

The method of claim 18, wherein the gradual shift of any out of phase pacing pulses comprises one of shifting the atrial pacing pulses relative to the ventricular pacing pulses and shifting the ventricular pacing pulses relative to the atrial pacing pulses.

### Claim 20 (depends on 19)

The method of claim 19, further including determining whether to shift the atrial pacing pulse relative to the ventricular pacing pulse or shift the ventricular pacing pulse relative to the atrial pacing pulse, the determination being based on a determination of which shift requires a lesser quantity of pacing cycles to shift the pacing pulses together in phase.