# US 7,609,868 B2 · Diagnostic imaging system and method providing information regarding blood flow in an anatomical anomaly

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- Number: US 7,609,868 B2
- Document ID: US7609868B2
- Status: Granted
- Kind: B2
- Application number: 11/348,657
- Filed: 2006-02-07
- Published: 2006-10-26
- Granted: 2009-10-27
- Earliest claimed: 2005-02-08
- Assignees: Siemens Aktiengesellschaft
- Inventors: Rainer Kuth; Axel Schreiber; Christoph Zindel
- Web page: https://patentgrep.com/patent/US7609868B2

## CPC

- A61B 5/42: {Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems (A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence)}
- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- A61B 6/507: {for determination of haemodynamic parameters, e.g. perfusion CT}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An imaging diagnosis system for generation of a three-dimensional image data set of an examination subject has an image acquisition unit that acquires three-dimensional raw data of the examination subject, an image reconstruction unit that generates a three-dimensional image data set from the three-dimensional raw data, an image processing unit that detects anatomical structures of the examination subject from the image data set, and a position determination unit that determines the position of an anomaly (identified by a diagnostician) in the anatomical structures of the examination subject in the image data set and generates position data for the image acquisition unit. The image acquisition unit acquires perfusion-sensitive raw data with the aid of the position data of the detected anomaly, which perfusion-sensitive raw data contain perfusion information of the identified anomaly.

## Claims

### Claim 1

A diagnostic imaging system comprising:
an image acquisition unit adapted to interact with an examination subject to acquire three-dimensional raw image data from the examination subject;
an image reconstruction unit connected to said image acquisition unit that generates a three-dimensional image dataset from said three-dimensional raw image data; and
a position determination unit and an input unit connected thereto, said input unit allowing a user to designate, in said three-dimensional image dataset, an anatomical anomaly in said examination subject, and said position determination unit, from said designation, generating position data supplied to said image acquisition unit to cause said image acquisition unit to acquire further data, selected from the group consisting of perfusion-sensitive data and angiographic raw data, from the examination subject at a location dependent on said position data, said further data containing information indicative of blood flow in said anatomical anomaly.

### Claim 2 (depends on 1)

A diagnostic imaging system as claimed in claim 1 wherein said image acquisition unit has an image acquisition unit coordinate system associated therewith and wherein said image dataset comprises image data having an image data coordinate system associated therewith, and wherein said position data have a position data coordinate system associated therewith, and wherein said position determination unit determines said position data in said image dataset in said image data coordinate system by applying an inverse of a transformation matrix to said position data and wherein said image reconstruction unit generates image data representing said anatomical anomaly by applying said transformation matrix to said position data.

### Claim 3 (depends on 1)

A diagnostic imaging system as claimed in claim 1 comprising an evaluation unit supplied with said further data, said evaluation unit generating a characteristic of blood flow in said anatomical anomaly from said further data, as said information indicative of blood flow in said anatomical anomaly.

### Claim 4 (depends on 3)

A diagnostic imaging system as claimed in claim 3 wherein said evaluation unit generates said characteristic from the group consisting of local blood volume in said anatomical anomaly, local blood flow through said anatomical anomaly, local average transit time of blood through said anatomical anomaly, local vessel permeability of said anatomical anomaly, and existence of vessels in said anatomical anomaly having a diameter greater than 5 mm.

### Claim 5 (depends on 1)

A diagnostic imaging system as claimed in claim 1 wherein said image acquisition unit acquires said three-dimensional raw data of the intestinal tract of said examination subject as a plurality of exposures, and comprising an image processing unit that detects the intestinal tract by segmentation, and wherein said anatomical anomaly is a polyp in the intestinal wall in said intestinal tract.

### Claim 6 (depends on 1)

A diagnostic imaging system as claimed in claim 1 wherein said image acquisition unit is a magnetic resonance scanner, and wherein said magnetic resonance scanner acquires said further data by implementing an imaging sequence selected from the group consisting of perfusion-sensitive T1-weighted imaging sequences and perfusion-sensitive T2*-weighted imaging sequences.

### Claim 7 (depends on 1)

A diagnostic imaging system as claimed in claim 1 wherein said image acquisition unit is a computed tomography scanner.

### Claim 8 (depends on 1)

A diagnostic imaging system as claimed in claim 1 comprising a contrast agent injector adapted to interact with the examination subject during acquisition of said further data, to inject contrast agent into the examination subject.

### Claim 9 (depends on 1)

A diagnostic imaging system as claimed in claim 1 comprising an evaluation unit supplied with information indicative of said blood flow in said anatomical anomaly that compares said information indicative of blood flow information of said anatomical anomaly with comparable blood flow information of comparable non-pathological tissue.

### Claim 10 (depends on 1)

A diagnostic imaging system as claimed in claim 1 comprising an evaluation unit that superimposes said information indicative of blood flow in said anatomical anomaly on a displayed anatomical image of said anatomical anomaly.

### Claim 11 (depends on 1)

A diagnostic imaging system as claimed in claim 1 comprising an image processing unit that detects anatomical structures of said examination subject from said image dataset.
