# US 7,609,059 B2 · Magnetic resonance method and apparatus with nuclear spins type-specific signal suppression > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 7,609,059 B2 - Document ID: US7609059B2 - Status: Granted - Kind: B2 - Application number: 12/046,807 - Filed: 2008-03-12 - Published: 2008-09-18 - Granted: 2009-10-27 - Earliest claimed: 2007-03-12 - Assignees: Siemens Aktiengesellschaft - Inventors: Timothy Hughes - Web page: https://patentgrep.com/patent/US7609059B2 ## CPC - G01R 33/5613: {Generating steady state signals, e.g. low flip angle sequences [FLASH]} - G01R 33/4828: {Resolving the MR signals of different chemical species, e.g. water-fat imaging} - G01R 33/5676: {Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction} - G01R 33/5607: {by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging} - G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12) ## Abstract A method in the form of a sequence for magnetic resonance imaging with which image data of a subject to be examined are acquired and with which signals of nuclear spins of a specific type are suppressed, includes the steps of (a) application of a suppression module to suppress signals of the nuclear spins of the specific type, (b) application of an acquisition module after a wait time to acquire measurement data, (c) repetition of the steps (a) and (b) one or more times, respectively after a repetition time and, (d) before the steps (a), (b) and (c), application of a spin preparation module that shifts a magnetization of the nuclear spins of the specific type into a steady state condition that is maintained through the application of the subsequent steps (a), (b) and (c). Alternatively, instead of the spin preparation module the first suppression module can be fashioned such that it has an RF pulse with a flip angle selected such that the magnetization of the nuclear spins of the specific type is shifted into a steady state condition. ## Claims ### Claim 1 A method for operating a magnetic resonance imaging apparatus comprising the steps of: (a) exposing an examination subject to a suppression module, comprised of a first set of at least one electromagnetic pulse, that suppresses magnetic resonance signals emanating from the examination subject that originate from nuclear spins of a predetermined type; (b) exposing the examination subject to an acquisition module, comprised of a second set of at least one electromagnetic pulse, after a wait time following exposure to said suppression module, to acquire magnetic resonance measurement data from the examination subject; (c) repeating steps (a) and (b) at least one time, each repetition occurring after a repetition time; and (d) before steps (a), (b) and (c), exposing the examination subject to a spin preparation module, comprised of a third set of at least one electromagnetic pulse, which shifts magnetization of said nuclear spins of said predetermined type into a steady state condition that is maintained during steps (a), (b) and (c). ### Claim 2 (depends on 1) A method as claimed in claim 1 comprising employing a third set of at least one electromagnetic pulse in said spin preparation module that shift the longitudinal magnetization of said nuclear spins of said predetermined type. ### Claim 3 (depends on 2) A method as claimed in claim 2 comprising employing a third set of at least one electromagnetic pulse as said spin preparation module that comprises an RF pulse. ### Claim 4 (depends on 3) A method as claimed in claim 3 comprising employing a third set of at least one electromagnetic pulse as said spin preparation module that comprises a single RF pulse. ### Claim 5 (depends on 3) A method as claimed in claim 3 comprising employing a third set of at least one electromagnetic pulse as said spin preparation module that comprises an adiabatic RF pulse. ### Claim 6 (depends on 1) A method as claimed in claim 1 comprising selecting said first set of at least one electromagnetic pulse that form said suppression module to suppress fat tissue protons as said nuclear spins of said predetermined type. ### Claim 7 (depends on 1) A method as claimed in claim 1 comprising employing a first set of at least one electromagnetic pulse as said suppression module that includes a radio-frequency pulse selected from the group consisting of a radio-frequency pulse for inversion of nuclear spins and an adiabatic RF pulse. ### Claim 8 (depends on 1) A method as claimed in claim 1 comprising employing a second set of at least one electromagnetic pulse in said acquisition module that comprises at least one RF pulse for excitation of nuclear spins and a subsequent subset of said second set for measurement data acquisition. ### Claim 9 (depends on 1) A method as claimed in claim 1 comprising formulating a pulse block comprising said first, second and third sets of at least one electromagnetic pulse and executing said pulse block multiple times. ### Claim 10 (depends on 9) A method as claimed in claim 9 comprising triggering each execution of said pulse block with a navigator echo. ### Claim 11 A method for magnetic resonance imaging comprising the steps of: (a) exposing an examination subject to a suppression module, comprising a first set of at least one electromagnetic pulse including at least one RF pulse, to suppress magnetic resonance signals originating from nuclear spins of a predetermined type; (b) exposing the examination subject to an acquisition module, comprised of a second electromagnetic pulse set, after a wait time following exposure of the examination subject to the suppression module, for acquisition of magnetic resonance measurement data; (c) repeating steps (a) and (b) at least one time, each repetition occurring after a repetition time; and (d) selecting a flip angle of said RF pulse in the first suppression module to shift magnetization of the nuclear spins of said predetermined type into a steady state condition that is maintained during the acquisition module and the suppression module in each repetition. ### Claim 12 (depends on 11) A method as claimed in claim 11 comprising selecting said flip angle of said RF pulse to shift the longitudinal magnetization of said nuclear spins of said predetermined type. ### Claim 13 (depends on 11) A method as claimed in claim 11 comprising, in each repetition of step (a) in step (c), generating said RF pulse as a pulse selected from the group consisting of RF pulses for inversion of the nuclear spins of the predetermined type and adiabatic RF pulses. ### Claim 14 (depends on 11) A method as claimed in claim 11 comprising selecting said first electromagnetic pulse set of said suppression module to suppress fat tissue protons as said nuclear spins of said predetermined type. ### Claim 15 (depends on 11) A method as claimed in claim 11 comprising employing a second set of electromagnetic pulses in said acquisition module that comprises at least one RF pulse for excitation of nuclear spins and a subsequent subset of said second set for measurement data acquisition. ### Claim 16 (depends on 11) A method as claimed in claim 11 comprising formulating a pulse block comprising said first, second and third sets of at least one electromagnetic pulse and executing said pulse block multiple times. ### Claim 17 (depends on 16) A method as claimed in claim 16 comprising triggering each execution of said pulse block with a navigator echo. ### Claim 18 A magnetic resonance apparatus comprising: a magnetic resonance scanner having a coil arrangement to expose an examination subject to electromagnetic pulses to excite nuclear spins in the examination subject and to acquire magnetic resonance signals resulting from the excited nuclear spins; and a control unit that operates said magnetic resonance scanner by (a) exposing an examination subject to a suppression module, comprised of a first set of at least one electromagnetic pulse, that suppresses magnetic resonance signals emanating from the examination subject that originate from nuclear spins of a predetermined type, (b) exposing the examination subject to an acquisition module, comprised of a second set of at least one electromagnetic pulse, after a wait time following exposure to said suppression module, to acquire magnetic resonance measurement data from the examination subject, (c) repeating steps (a) and (b) at least one time, each repetition occurring after a repetition time, and (d) before steps (a), (b) and (c), exposing the examination subject to a spin preparation module, comprised of a third set of at least one electromagnetic pulse, that shifts magnetization of said nuclear spins of said predetermined type into a steady state condition that is maintained during steps (a), (b) and (c). ### Claim 19 A magnetic resonance apparatus comprising: a magnetic resonance scanner having a coil arrangement to expose an examination subject to electromagnetic pulses to excite nuclear spins in the examination subject and to acquire magnetic resonance signals resulting from the excited nuclear spins; and a control unit that operates said magnetic resonance scanner by (a) exposing an examination subject to a suppression module, comprising a first set of at least one electromagnetic pulse including at least one RF pulse, to suppress magnetic resonance signals originating from nuclear spins of a predetermined type, (b) exposing the examination subject to an acquisition module, comprised of a second electromagnetic pulse set, after a wait time following exposure of the examination subject to the suppression module, for acquisition of magnetic resonance measurement data, (c) repeating steps (a) and (b) at least one time, each repetition occurring after a reaction time, and (d) selecting a flip angle of said RF pulse in the first suppression module to shift magnetization of the nuclear spins of said predetermined type into a steady state condition that is maintained during the acquisition module and the suppression module in each repetition.