Microorganism producing 5′-xanthylic acid
AssigneeCj Cheiljedang Corporation
InventorsYoung-Hoon Park, Jea-Young Chang, Jin-Nam Lee, Ki-Hoon Oh, Jeong-Hwan Kim, Yoon-Suk Oh, Jae-Ick Sim
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Abstract
The invention relates to a microorganism, obtained by treating Corynebacterium ammoniagenes KCCM 10488 producing 5′-Xanthylic acid as parent strain with UV radiation and mutation Derivatives such as N-methyl-N′nitro-N-nitrosoguanidine (NTG), Having a resistance to 5-fluorotryptophan which enhances Biosynthesis of N5-N10-tetrahydrofolate used for transferring Two formyl group during the process of puring biosynthesis, making It possible to accumulate 5′xanthylic acid in culture medium at a high Yield and high concentration rate same period of fermentation.
Claims2
An isolated microorganism CJXFT 0301 (Accession Number:
- KCCM-10530) producing 5′-xanthylic acid, which is a mutant strain of Corynebacterium ammoniagenes having a resistance to 5-fluorotryptophan.
Dependencies are inferred from the claim text.