# US 7,607,561 B2 · Guide wire

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 7,607,561 B2
- Document ID: US7607561B2
- Status: Granted
- Kind: B2
- Application number: 11/790,845
- Filed: 2007-04-27
- Published: 2007-08-30
- Granted: 2009-10-27
- Earliest claimed: 2002-08-08
- Assignees: Terumo Kabushiki Kaisha
- Inventors: Hiraku Murayama; Akihiko Umeno; Jun Iwami; Yutaka Itou; Youki Aimi
- Web page: https://patentgrep.com/patent/US7607561B2

## CPC

- A61M 25/09: Guide wires
- B23K 31/02: relating to soldering or welding
- A61M 2025/09091: {where a sheath surrounds the coil at the distal part}
- A61M 2025/0915: {having features for changing the stiffness}
- Y10T 29/49888: Subsequently coating
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- B23K: SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

A guide wire includes a wire member having a first wire disposed on the distal side of the guide wire, and a second wire disposed on the proximal side from the first wire. The second wire is made from a material having an elastic modulus larger than that of the first wire. For example, the first wire is made from a superelastic alloy, and the second wire is made from a stainless steel. The first wire is joined to the second wire at a welded portion by welding. A coil is disposed on the distal side from the first wire. A cover layer is formed on the outer peripheral surface of the wire member in such a manner as to cover at least the welded portion. The cover layer is made from a material capable of reducing the friction of the cover layer, for example, a fluorocarbon resin or a hydrophilic material, to thereby improve the sliding performance of the guide wire. Such a guide wire is excellent in operationality and kink resistance.

## Claims

### Claim 1

A method of manufacturing a guide wire comprising:
welding a first wire to a second wire at a welded portion to form a wire member in which the first wire is disposed on a distal side of the second wire;
coating an outer periphery of the wire member at the welded portion with a polymer cover layer while the wire member is not heated;
coating the outer periphery of the wire member on a distal side of the cover layer with a distal-side polymer cover layer while heating the wire member.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the first wire possesses a connection end face that is perpendicular to an axial extent of the first wire, the second wire possessing a connection end face that is perpendicular to an axial extent of the second wire, the first and second wires being welded to one another while the connection end face of the first wire abuts the connection end face of the second wire.

### Claim 3 (depends on 1)

The method according to claim 1, further comprising covering the outer periphery of the wire member on a proximal side of the cover layer with a proximal-side cover layer while heating the wire member.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the second wire possesses a modulus of elasticity that is greater than the modulus of elasticity of the first wire.

### Claim 5 (depends on 1)

The method according to claim 1, wherein the welding is butt-welding.

### Claim 6 (depends on 1)

The method according to claim 1, wherein the polymer cover layer coating the outer periphery of the wire member at the welded portion comprises silicone.

### Claim 7 (depends on 1)

The method according to claim 1, wherein the distal-side polymer cover layer comprises a fluorocarbon resin.

### Claim 8 (depends on 1)

The method according to claim 1, wherein a distal end of the polymer cover layer coating the outer periphery of the wire member at the welded portion is joined to a proximal end of the distal-side polymer cover layer.

### Claim 9 (depends on 1)

The method according to claim 1, wherein the polymer cover layer coating the outer periphery of the wire member at the welded portion is made of a material different from material of which the distal-side polymer cover layer is made.

### Claim 10 (depends on 9)

The method according to claim 9, wherein a distal end of the polymer cover layer coating the outer periphery of the wire member at the welded portion is joined to a proximal end of the distal-side polymer cover layer.