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US 7,605,239 B2Granted
Skeletal-targeted radiation to treat bone-associated pathologies
AssigneePoniard Pharmaceuticals, Inc.
InventorAlan R. Fritzberg
Life of this patent
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Abstract
The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
Claims9
A therapeutic pharmaceutical dosage form comprising:
- (a) an amount of 153Sm-EDTMP effective for suppressing the bone marrow of a human;
- (b) an effective antiradiolytic amount of a pharmaceutically acceptable radioprotectant;
- and
- (c) an aqueous vehicle.
1 more element
Dependencies are inferred from the claim text.