Process for producing an amide compound
AssigneeNihon Medi-Physics Co., Ltd.
InventorsNaoyuki Takano, Daisaku Nakamura
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Abstract
There is disclosed a process for producing an amide compound, which process is characterized in that a compound having an amino group are reacted with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopolycarboxylic acid.
Claims17
A process for producing an amide compound, which comprises reacting a compound having an amino group with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopolycarboxylic acid,
- wherein the polyaminopolycarboxylic acid anhydride is added to a mixture of the compound having an amino group and the polyaminopolycarboxylic acid, or the compound having an amino group and the polyaminopolycarboxylic acid anhydride are added to the polyaminopolycarboxylic acid,
- wherein the polyaminopolycarboxylic acid anhydride is ethylenediaminetetraacetic dianhydride, ethylenediaminetetraacetic acid monoanhydride, diethylenetriaminepentaacetic acid dianhydride, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic dianhydride, or 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid monoanhydride;
- and
- wherein the polyaminopolycarboxylic group of both said acid and said acid anhydride are the same.
A process for producing an amide compound, which comprises reacting a compound having an amino group with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopolycarboxylic acid;
- wherein the compound having an amino group is a chitosan tri- to deca-saccharide,
- wherein the polyaminopotycarboxylic acid anhydride is added to a mixture of the compound having an amino group and the polyaminopolycarboxylic acid, or the compound having an amino group and the polyaminopolycarboxylic acid anhydride are added to the polyaminopolycarboxylic acid,
- wherein the polyaminopolycarboxylic acid anhydride is ethylenediaminetetraacetic dianhydride, ethylenediaminetetraacetic acid monoanhydride, diethylenetriaminepentaacetic acid dianhydride, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic dianhydride, or 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid monoanhydride;
- and
- wherein the polyaminopolycarboxylic group of both said acid and said acid anhydride are the same.
A process for producing an amide compound, which comprises reacting a compound having an amino group with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopoilycarboxylic acid;
- wherein the polyaminopolycarboxylic acid is ethylenediamine-tetraacetic acid, diethylenetriamine-pentaacetic acid, or 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid,
- wherein the polyaminopdycarboxylic acid anhydride is added to a mixture of the compound having an amino group and the polyaminopolycarboxylic acid, or the compound having an amino group and the polyaminopolycarboxylic acid anhydride are added to the polyaminopolycarboxylic acid;
- and
- wherein the polyaminopolycarboxylic group of both said acid and said acid anhydride are the same.
A process for producing an amide compound, which comprises reacting a compound having an amino group with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopolycarboxylic acid and a base,
- wherein the polyaminopolycarboxylic acid anhydride is added to a mixture of the compound having an amino group and the polyaminopolycarboxylic acid, or the compound having an amino group and the polyaminopolycarboxylic acid anhydride are added to the polyaminopolycarboxylic acid,
- wherein the polyaminopolycarboxylic acid anhydride is ethylenediaminetetraacetic dianhydride, ethylenediaminetetraacetic acid monoanhydride, diethylenetriaminepentaacetic acid dianhydride, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic dianhydride, or 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid monoanhydride;
- and
- wherein the polyaminopolycarboxylic group of both said acid and said acid anhydride are the same.
Dependencies are inferred from the claim text.