Albumin-based colloid composition and method of use in treating hypovolemia and multiorgan dysfunction
AssigneeMedical College of Ohio
InventorsRagheb Assaly, John D. Dignam, Joseph I. Shapiro
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Abstract
A composition comprising an albumin-based colloid and its use in treating hypovolemic conditions such as capillary leak syndrome and shock are disclosed.
Claims6
An in vivo method of treating a hypovolemic condition in a patient having a hypovolemic condition and/or multiorgan dysfunction resulting from a hypovolemic condition, comprising administering a therapeutic amount of polyethylene glycol-albumin colloid composition having a molecular weight greater than 80 KD to said patient, wherein the polyethylene glycol-albumin colloid composition reduces a risk of organ injury and treats hypovolemic conditions by restoring vascular volumes.
An in vivo method of pretreating injury or multiorgan dysfunction due to a hypovolemic condition, comprising administering a therapeutic amount of a polyethylene glycol-albumin colloid composition to a patient at risk of injury or multiorgan dysfunction due to a hypovolemic condition, wherein the polyethylene glycol-albumin colloid composition reduces a risk of organ injury and treats hypovolemic conditions by restoring vascular volumes.
Dependencies are inferred from the claim text.