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US 7,605,128 B2Granted
Neurogenerative or neurotrophic factors for mitigating a symptom of ischemia
AssigneeBuck Institute for Age Research
InventorsDavid C. Greenberg, Kunlin Jin, Xiao Ou Mao, Lin Xie, Yunjuan Sun, Jocelyn Childs
Life of this patent
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Abstract
This invention pertains to the identification of neurogenerative and/or neurotrophic factors that can induce migration of stem cells to neural tissue and/or induce proliferation and/or differentiation of such cells into neurons. Such agents include, but are not limited to stem cell factor (SCF), heparin binding EGF (HB-EGF), and VEGF.
Claims13
A method of mitigating one or more symptoms associated with acute or chronic neurodegenerative condition in a mammal, said method comprising:
- administering to said mammal stem cell factor in an amount sufficient to induce neuroproliferation from endogenous cells in said mammal.
Dependencies are inferred from the claim text.