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US 7,604,947 B2Granted
Detection and modulation of cancer stem cells
AssigneeCornell Research Foundation, Inc.
InventorLorraine J. Gudas
Life of this patent
Estimating the term…
Abstract
The invention relates to method for detecting and modulating the expression and activity of REX-1. As described herein, REX-1 is expressed in certain cancer cells, including cancer stem cells. The invention also provides methods for detecting and/or treating cancer.
Claims4
A method for detecting carcinoma in a tissue sample comprising contacting the tissue sample with an anti-REX-1 antibody that can bind a REX-1 protein of SEQ ID NO:
- 1 and detecting whether a significantly lower amount of the antibody binds to an REX-1 protein within cells in the test tissue sample relative to a control, non-cancerous tissue sample to thereby detect carcinoma in a tissue sample.
Dependencies are inferred from the claim text.