Back to results
US 7,604,940 B1Granted
Compositions and methods for analyzing isolated polynucleotides
AssigneeApplied Biosystems, LLC
InventorKarl Voss
Life of this patent
Estimating the term…
Abstract
Compositions and methods of use are disclosed for the analysis of polynucleotides isolated in individual reaction compartments.
Claims22
A method of analyzing the contents of a microcapsule comprising inserting the microcapsule into a capillary of a capillary electrophoresis system, and analyzing one or more molecules released from the microcapsule in the capillary.
A method of analyzing the contents of a plurality of microcapsules comprising inserting the plurality of microcapsules into a plurality of capillaries of an electrophoresis system, and analyzing the contents of the capsules.
A sequencing method comprising:
- a) clonally amplifying a plurality of target polynucleotides in a plurality of aqueous compartments of an inverse emulsion, wherein the clonally amplified target polynucleotides are derived from a single polynucleotide molecule;
- and
- b) sequencing the amplification products of a) in a plurality of microcapsules.
Dependencies are inferred from the claim text.