US 7,604,822 B2Granted

Injectable solution with anti-inflammatory effect and process for manufacturing the same

AssigneeImunomod S.R.L.

InventorElena Ionascu

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Abstract

An anti-inflammatory injectable solution is prepared from Symphytum officinale roots by cutting and drying of the vegetal material; calcining it at a temperature of 550-600° C., over a period of 3 to 4 hours; dissolving the ash obtained in distilled water at a ratio of 1:100 to form a solution, the obtained solution is filtered under vacuum, followed by filtration through milipor or semper filters to produce a filtrate and the filtrate is subjected to boiling evaporation to produce a liquid having a viscosity of 6.57±0.5 cP; and then drying a thin layer of the liquid so producedat a temperature of 200-250° C., over a period of 5-15 minutes until a white powder is obtained; and thereafter dissolving said white powder in distilled water in amount of 1 to 700 mg to 100 ml distilled water or saline solution.

Claims7

Dependent claims

A method for producing an injectable solution, comprising the following steps:

a) cutting and drying Symphytum officinale roots;
b) calcination of the dried cut roots obtained in stage (a) at a temperature of 550-600° C., over a period of 3 to 4 hours to produce ash;
c) dissolving the ash obtained after calcination in distilled water to produce a solution,
d) filtering the obtained solution under vacuum, followed by additional filtration through Sempore filters and then through Millipore filters to produce a filtrate;
e) drying the filtrate by boiling evaporation to produce a liquid having a high viscosity;
and then further drying a thin layer of the high viscosity liquid at a temperature of 200-250° C., over a period of 5-15 minutes until a white powder is obtained;
and
f) dissolving the white powder in distilled water or a saline solution to produce injectable solution.

5 more elements

Dependencies are inferred from the claim text.