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US 7,604,185 B2Granted
Generation of therapeutic microfoam
AssigneeBTG International Limited
InventorsTariq Osman, Sheila Bronwen Flynn, David Dakin Iorwerth Wright, Anthony David Harman, Timothy David Boorman
Life of this patent
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Abstract
Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.
Claims35
A microfoam comprising
- a gas component comprising a physiologically acceptable blood dispersible gas comprising 10 to 90% vol/vol carbon dioxide or a mixture of 10 to 90% vol/vol carbon dioxide with the remaining gas oxygen,
- and an aqueous sclerosant liquid suitable for use in sclerotherapy of blood vessels,
- wherein the microfoam has a density ranging from 0.07 g/ml to 0.19 g/ml.
A microfoam comprising
- a gas component comprising a physiologically acceptable blood dispersible gas comprising 20 to 30% vol/vol carbon dioxide or a mixture of 20 to 30% vol/vol carbon dioxide and 70 to 80% vol/vol oxygen,
- and an aqueous sclerosant liquid comprising polidocanol in an aqueous carrier or sodium tetradecylsulfate (STS) in an aqueous carrier,
- wherein the microfoam has a density ranging from 0.09 g/ml to 0.16 g/ml.
Dependencies are inferred from the claim text.