Back to results
US 7,598,403 B2Granted
Synthesis of chromanones
AssigneeUniversity of South Carolina Research Foundation
InventorsBrian A. Salvatore, Ferdinand C. Solis
Life of this patent
Estimating the term…
Abstract
Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.
Claims17
A chromanone corresponding to Formula 21:
- wherein
- R5 is amino or nitro;
- R6 is amino, hydroxy, halo, perfluorinated sulfonic ester, R61C(O)—, R62C(O)O—, R61C(O)NH—, R62CHCH— or R62CC—;
- R21 and R22 are independently hydrogen, alkyl, or aryl;
- R61 is hydrogen, heterocyclo, alkoxy, heterocyclooxy, amino, or halo, and
- R62 is hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclo, alkoxy, heterocyclooxy, amino, or halo.
3 more elements
The chromanone of claimi wherein R6 is R62CHCH— or R62CC—.
A chromanone corresponding to Formula 62 or 67
- wherein
- R62 is hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclo, alkoxy, heterocyclooxy, amino or halo;
- and
- R21 and R22 are independently hydrogen, alkyl, or aryl.
1 more element
Dependencies are inferred from the claim text.