Polygonal nanostructures of polynucleic acid multi-crossover molecules and assembly of lattices based on double crossover cohesion
AssigneeNew York University
InventorsNadrian C. Seeman, Baoquan Ding, Pamela E. Constantinou, Tong Wang, Jens Kopatsch, Xiaoping Zhang, Ruojie Sha, Lisa Israel
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Abstract
Robust nucleic acid arrays and lattices are assembled based on double crossover cohesion of polygonal units whose edges are composed of nucleic acid multi-crossover domains.
Claims18
A polynucleic acid structure, comprising a polygonal unit whose edges are parallel helices of connected nucleic acid multi-crossover domains along their helix axes, each of said edges having at least one free end with two parallel helices, wherein each of said two parallel helices at one free end of each of said edges terminate in a cohesive end to provide a double cohesive end on said one free end.
Dependencies are inferred from the claim text.