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US 7,598,068 B2Granted
Chondroitin polymerase and DNA encoding the same
AssigneeSeikagaku Corporation
InventorsToshio Ninomiya, Nobuo Sugiura, Koji Kimata
Life of this patent
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Abstract
A chondroitin polymerase having such properties that it transfers GlcUA and GalNAc alternately to a non-reduced terminal of a sugar chain from a GlcUA donor and a GalNAc donor, respectively, and the like; and a process for producing the chondroitin polymerase.
Claims16
An isolated protein that comprises SEQ ID NO:
- 2, a fragment of SEQ ID NO:
- 2, or an amino acid sequence identical to SEQ ID NO:
- 2 except that it has 1 to 30 of its amino acid residue(s) deleted, or substituted, or 1 to 30 amino acid residues inserted within the sequence of SEQ ID NO:
- 2;
- wherein said isolated protein has chondroitin polymerase activity;
- and
- wherein said isolated protein is not membrane-bound.
4 more elements
An isolated protein that comprises SEQ ID NO:
- 2, a fragment of SEQ ID NO:
- 2, or an amino acid sequence identical to SEQ ID NO:
- 2 except that it has 1 to 30 of its amino acid residue(s) deleted, or substituted, or 1 to 30 amino acid residues inserted within the sequence of SEQ ID NO:
- 2;
- wherein said isolated protein has chondroitin polymerase activity;
- and
- wherein said isolated protein is not membrane-bound and is soluble in a culture medium.
4 more elements
Dependencies are inferred from the claim text.