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US 7,597,885 B2Granted
Tissue engineered biomimetic hair follicle graft
AssigneeAderans Research Institute, Inc.
InventorsThomas H. Barrows, Stephen A. Cochran, Bryan Marshall
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AssigneeAderans Research Institute, Inc.
InventorsThomas H. Barrows, Stephen A. Cochran, Bryan Marshall
Estimating the term…
The present invention relates to an improved scaffold which is constructed to mimic the architecture of the native hair follicle. The present invention also relates to the use of specific compositions and methods of manufacture to produce scaffolds that combine biocompatibility with the desired rates of bioabsorption. In another embodiment, the present invention relates to a process for manufacturing a biomimetic hair follicle graft and a method for seeding the graft with cells and implanting the graft into the skin where the growth of a new hair shaft is desired. A further embodiment of the present invention relates to a method for hair multiplication in which cells are multiplied in culture and aliquoted into a multitude of bioabsorbable scaffolds in combination with cultured keratinocytes or other allogenic cells.
A graft comprising (1) a bioabsorbable filament having an exterior surface and a central lumen having an interior wall opening through the exterior surface, wherein the central lumen comprises a hydrophilic interior effective to wick the cells into the filament;
A graft comprising (1) a bioabsorbable filament having a central lumen having an interior wall;
Dependencies are inferred from the claim text.