Sunscreen safety and efficacy enhancement
AssigneeBioderm Research
InventorShyam K Gupta
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Abstract
The present invention discloses safety and efficacy enhancement of sunscreens with certain heterocyclic base complexes of manganese via urocanate pathway modulation. The present invention also discloses a method for topical application of said complexes, which causes the reduction of topical peroxide including hydrogen peroxide, the reduction of topical inflammation including sunburn, increased sun protection of skin, the reduction of skin wrinkles, comprehensive protection from UVA, UVB, and UVC, and reduction of radiation-initiated inflammation.
Claims20
A heterocyclic complex comprising manganese, wherein said manganese is covalently bound to at least two oxygen atoms and, wherein, said base having at least one nitrogen atom in its ring structure coordinately bound to said manganese;
- wherein said complex is selected from the group consisting of manganese cis-urocanate, (I);
- manganese cis-urocanate gluconate, (II);
- manganese cis-urocanate glycinate, (III),
- and combinations thereof.
Dependencies are inferred from the claim text.