Water soluble quantum dots
AssigneeDrexel University
InventorsWei-Heng Shih, Wan Y. Shih, Hui Li, Melissa Colleen Schillo
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AssigneeDrexel University
InventorsWei-Heng Shih, Wan Y. Shih, Hui Li, Melissa Colleen Schillo
Estimating the term…
An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm to 700 nm. Highly luminescent metal sulfide (MS) QDs are produced via an aqueous synthesis route. MS QDs are capped with thiol-containing charged molecules in a single step. The resultant MS QDs exhibit the distinctive excitonic photoluminescence desired of QDs and can be fabricated to avoid undesirable broadband emissions at higher wavelengths. This provides a significant improvement over the present complex and expensive commercial processes for the production of QDs. The aqueous QDs are stable in biological fluids over a long period of time. In addition, nontoxic ZnS QDs have been produced with good photoluminescence properties by refluxing the ZnS QD suspensions over a period of time.
A water soluble quantum dot suitable for bioconjugation consisting essentially of:
Quantum dots suitable for bioconjugation, said quantum dots made by a process comprising the steps of:
A water soluble quantum dot suitable for bioconjugation comprising cadmium sulfide and one or more metal sulfides selected from the group consisting of:
Dependencies are inferred from the claim text.