System of loading beneficial agent to a prosthesis by fluid-jet
AssigneeAbbott Laboratories
InventorsDonald Verlee, Peter Tarcha, Keith Cromack, Richard Quint
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Abstract
An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The method of loading beneficial agent includes dispensing beneficial agent in a raster format and/or an off-axis format along a dispensing path.
Claims9
A system for loading beneficial agent onto a prosthesis for delivery within a lumen, the system comprising:
- a holder for supporting a prosthesis to be deployed within a lumen;
- a fluid-dispenser having a dispensing element capable of dispensing beneficial agent in discrete droplets, each droplet having a controlled trajectory, the dispensing element and the holder being movable relative to each other;
- a driver for creating relative movement between the dispensing element and the holder;
- a controller in communication with the driver to define a dispensing path for dispensing discrete droplets of beneficial agent in a raster format, the controller also in communication with the dispensing element to selectively dispense beneficial agent from the dispensing element to a predetermined portion of a prosthesis supported by the holder along the dispensing path;
- and
- a beneficial agent detector in communication with the controller configured to determine an amount of beneficial agent loaded on a prosthesis, the beneficial agent detector being configured to image the prosthesis to determine an amount of identifiable marker loaded onto the prosthesis to determine a corresponding amount of beneficial agent loaded to the prosthesis.
Dependencies are inferred from the claim text.