Albumin fusion proteins
AssigneesHuman Genome Sciences, Inc., Delta Biotechnology Limited
InventorsCraig A. Rosen, William A. Haseltine, David J. Ballance, Andrew J. Turner, Steven M. Ruben
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Abstract
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.
Claims83
An albumin fusion protein comprising an interferon alpha polypeptide fused to an albumin polypeptide wherein said albumin fusion protein is produced from an isolated host cell comprising Construct ID 3165.
An albumin fusion protein comprising an interferon alpha polypeptide fused to an albumin polypeptide, wherein said albumin fusion protein is produced from an isolated host cell comprising the construct contained in ATCC Deposit No. PTA-4670.
An albumin fusion protein produced from an isolated host cell comprising a construct encoding an interferon alpha polypeptide fused to an albumin polypeptide, wherein said albumin fusion protein comprises amino acids 25 to 774 of SEQ ID NO:1300.
Dependencies are inferred from the claim text.