Compounds and compositions to control abnormal cell growth

A method of treating a patient with a tumor, the method comprising administering to the patient a pharmaceutical comprising a heterocyclic compound having one or two quaternary ammonium groups to reduce the volume of the tumor, the compound having the formula:

• wherein R1 and R3-8 are independently hydrogen or C1-C26 straight, branched or cyclic alkanes or alkenes, aromatic hydrocarbons, alcohols, ethers, aldehydes, ketones, carboxylic acids, amines, amides, nitriles or five—and/or six-membered heterocycle;
• wherein R9 and R10 considered together are ═O or ═CH-L-N+(R11, R12, R13) (where -L-N+(R11, R12, R13) is defined below) or R9 and R10 considered independently are —OH or L-N+(R11, R12, R13);
• wherein R2 is represented by the formula:
• —X-L-N+(R11, R12, R13,) Z−;
• —X-N+(R11, R12, R13);
• CH3;
• or Hydrogen;
• wherein V may be —S— or —Se— or —C— or —O— or —N;
• wherein Y may be —S—or —Se— or —C— or —O— or —N;
• wherein -L-N+(R11, R12, R13)Z− can be linked to V or Y if V or Y are —N or can be linked to V and Y if V and Y are both —N;
• wherein X is —CH2—, —OCH2—, —CH2O—, —SCH2— or —CH2S—;
• wherein L is a C1-C4 straight alkane, alkene, thiol, ether, or amine;
• wherein R11, R12 and R13 are represented independently by C1-C4 straight alkanes, alkenes, thiols, amines, ethers, alcohols;
• and
• wherein Z− is Cl−, Br− or I−.