Embolization
AssigneeBoston Scientific Scimed, Inc.
InventorsMarcia Buiser, Marc Bellisario, David Knapp, Stephan Mangin, Janel Lanphere
Life of this patent
Estimating the term…
Abstract
Embolic polymer particles are described. For example, the particles include pores such that the predominant size of pores near the center of the particles is greater than the predominant size of pores adjacent to periphery of the particle
Claims48
An embolic composition, comprising:
- substantially spherical embolic particles having a diameter of about 1500 micron or less, the particles comprising polyvinyl alcohol, and including a first region including pores having a first predominant pore size and a second region surrounding the first region and including pores having a second predominant pore size,
- wherein the first predominant pore size is larger than the second predominant pore size.
A method comprising administering to a patient in need of embolization a therapeutically effective amount of substantially spherical embolic polymer particles having a diameter of 1500 microns or less, the particles comprising polyvinyl alcohol, and including a first region including pores having a first predominant pore size and a second region surrounding the first region and including pores having a second predominant pore size,
- wherein the first predominant pore size is larger than the second predominant pore size.
An embolic composition, comprising:
- embolic polymer particles having a diameter of about 1500 micron or less, and including a surface including pores with a predominant pore size of about 2 micron or less and pores interior to said surface with a predominant pore size of about 10 micron or more.
An embolic composition comprising:
- embolic polymer particles having a diameter of about 1500 microns or less, and including a surface region from about 0.8r to r, the predominant pore size in the surface region being smaller than the predominant pore size in a region C to 0.3r, and r is a radius of the particles.
An embolic composition, comprising:
- embolic particles having a diameter of about 1500 microns or less, and including a surface region defined primarily by surface region pores and an interior region defined primarily by interior region pores, wherein the surface region pores are smaller than the interior region pores.
Dependencies are inferred from the claim text.