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US 7,585,319 B2Granted
Self-aggregating protein compositions and use as sealants
AssigneeMaquet Cardiovascular LLC
InventorsDan Castro, Al Kuehn, Moon Hae Sunwoo
Life of this patent
Estimating the term…
Abstract
An implantable member for use in the body is provided herein. This implantable member includes a porous biocompatible substrate; the substrate having at least one surface sealed fluid-tight with self-aggregating protein particles of substantially the same diameter range. The self-aggregated protein particles are formed from a deposited aqueous slurry of the protein particles.
Claims16
An implantable member for use in the body comprising:
- a porous biocompatible substrate;
- the substrate having at least one surface sealed fluid-tight with a non-crosslinked sealant, said sealant comprising self-aggregating purified protein particles of substantially uniform particle size, said protein particles being obtained by cryogenically milling said protein in a purified form suitable for implantation, wherein said sealant of the final product has not been exposed to a cross-linking agent.
Dependencies are inferred from the claim text.