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US 7,582,768 B2Granted
Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
AssigneeTeva Pharmaceutical Industries Ltd.
InventorsJudith Aronhime, Revital Lifshitz-Liron
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Abstract
The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
Claims3
Crystalline solid zoledronic acid (Form XX) characterized by a powder X-ray diffraction pattern with peaks at 12.2°, 19.3°, 20.2°, 21.3°, 25.1°, 27.2°, 11.4°,14.9°,15.5°,17.2°,18.2°, and 30.5°±0.2°2θ.
Dependencies are inferred from the claim text.