Salt and crystalline forms of (2R)-anti-5-{3-[4-(10,11-difluoromethanodibenzosuber-5-YL)piperazin-1-YL]-2-hydroxypropoxy}quinoline
AssigneeEli Lilly and Company
InventorsJulie Kay Bush, Susan Marie Reutzel-Edens
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Abstract
The present invention provides methods of treating leukemia comprising administration of a resistance modulating amount of a compound having the formula (2r)-anti-5-{3-[4-(10,11-difluoromethano-dibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy}quinoline 2.5 hydrochloride.
Claims8
A method of treatment for a drug resistant disease comprising coadministering to a mammal in need thereof a resistance modulating amount of a compound of the formula (2R)-anti-5-{3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy}quinoline 2.5 hydrochloride, and an effective amount of a treatment drug for said drug resistant disease, wherein the drug resistant disease is leukemia.
Dependencies are inferred from the claim text.