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US 7,582,756 B2Granted
3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
AssigneesSugen, Inc., Pharmacia & Upjohn Company
InventorsHuiping Guan, Congxin Liang, Li Sun, Peng Cho Tang, Chung Chen Wei, Tomas Vojkovsky, Qingwu Jin, Paul M. Herrinton, Michael A. Mauragis
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Abstract
The present invention provides a method to make a pyrrole substituted 2-indolinone compound of the formula
Claims3
A method of making a compound of the formula
- or a pharmaceutically acceptable salt thereof, comprising reacting a compound of the formula
- with a compound of the formula
- and a compound of the formula
- in the presence of a suitable base and in a suitable solvent.
1 more element
Dependencies are inferred from the claim text.