Agents, which inhibit apoptosis in cells that are involved in wound healing
AssigneeDermatools Biotech GmbH
InventorsMark Freyberg, Peter Friedl, Dirk Kaiser
Life of this patent
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Abstract
The invention relates to the use of substances as a fundamental constituent in wound healing agents. The invention is characterised in that said substances bond to either IAP and/or integrin αvβ3 and/or thrombuspondin-1 in such a way that the bond between thrumbospondin-1 and IAP and/or integrin αvβ3 is inhibited.
Claims21
A medicament for promoting wound healing, comprising a substance that bind to at least one of integrin-associated protein (IAP), integrin αvβ3, and thrombospondin 1, wherein said substance inhibits binding between thrombospondin 1 and at least one of IAP and integrin αvβ3, and inhibit apoptosis characterized by nuclear fragmentation of cells, wherein said substance is a peptide consisting of the amino acid sequence depicted in SEQ ID NO 1.
Dependencies are inferred from the claim text.