Synergistic mixtures of 1,2-alkane diols
AssigneeSymrise AG
InventorsGerhard Schmaus, Sabine Lange, Holger Joppe
Life of this patent
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Abstract
The use of mixtures of two, three or more straight-chain 1,2-alkanediols, the chains lengths of which (i) are different and (ii) in each case are in the range of 5 to 10 C atoms, as antimicrobial active compounds is described. Compared with the pure 1,2-alkanediols, the mixtures have a synergistically intensified action.
Claims22
An antimicrobial composition, comprising an antimicrobial effective amount of a mixture of 1,2-alkanediols consisting of two or more straight chain 1,2-alkanediols having chain lengths that (i) are different and (ii) in each case are in the range of 5 to 10 C atoms, wherein said mixture of 1,2-alkanediols exhibits an antimicrobial effect characterized by a Kull value of less than 1.
An antimicrobial composition comprising an antimicrobial effective amount of a mixture of 1,2-alkanediols consisting of at least one of:
- (a) 1,2-hexanediol and 1,2-octanediol,
- (b) 1,2-hexanediol and 1,2-decanediol,
- (c) 1,2-pentanediol, 1,2-hexanediol and 1,2-octanediol,
- (d) 1,2-hexanediol, 1,2-octanediol and 1,2-decanediol and
- (e) 1,2-pentanediol, 1,2-hexanediol and 1,2-decanediol
- as antimicrobial active compounds, the proportions of the said diols in the mixture of 1,2-alkanediols being set such that a Kull value of less than 1.0 for the antimicrobial effect exhibited by said mixture of 1,2-alkanediols results.
An antimicrobial composition comprising an antimicrobial effective amount of a mixture of 1,2-alkanediols consisting of two or more straight chain 1,2-alkanediols having chain lengths of which (i) are different and (ii) are in the range of 5 to 10 C atoms, wherein the proportions of said diols in the mixture of 1,2-alkanediols are set such that a Kull value of less than 1.0 for the antimicrobial effect exhibited by said mixture of 1,2-alkanediols results for at least one of:
- (a) a cosmetic treatment of microorganisms causing body odour,
- (b) a cosmetic treatment of microorganisms causing acne,
- (c) a cosmetic treatment of microorganisms causing mycoses,
- (d) a treatment of microorganisms on or in inanimate material and
- (e) preservation of a perishable product.
An antimicrobially active pharmaceutical composition consisting of an antimicrobial effective amount of a mixture of 1,2-alkanediols consisting of two or more straight chain 1,2-alkanediols having chain lengths of which (i) are different and (ii) are in the range of 5 to 10 C atoms, wherein the proportions of the said diols in the mixture of 1,2-alkanediols are such that said mixture of 1,2 alkanediols exhibits an antimicrobial effect characterized by a Kull value of less than 1.0.
An antimicrobial composition, comprising:
- (a) as antimicrobial active compound, a mixture of two, three or more straight-chain 1,2-alkanediols, the chain lengths of which (i) are different and (ii) in each case are in the range of 5 to 10 C atoms, and
- (b) an excipient compatible with the said mixture, wherein the proportions of the said diols in the mixture are set such that a Kull value of less than 1.0 for the antimicrobial effect exhibited by said mixture of 1,2-alkanediols results.
An antimicrobial composition, comprising
- (a) an antimicrobial effective amount of a mixture of two, three or more straight-chain 1,2-alkanediols, the chain lengths of which (i) are different and (ii) in each case are in the range of 5 to 10 C atoms, and
- (b) a preservative other than straight-chain 1,2-alkanediols, wherein the proportions of the said diols in the mixture are set such that a Kull value of less than 1.0 for the antimicrobial effect exhibited by said mixture of 1,2-alkanediols results.
Dependencies are inferred from the claim text.