2-phenylpyran-4-one derivatives as selective COX-2 inhibitors

A compound of formula (I):

• wherein
• R1 represents an alkyl group;
• R2 represents a group chosen from alkyl, C3-C7 cycloalkyl, pyridyl, thienyl, naphthyl, tetrahydronaphthyl, indanyl, and a phenyl group;
• wherein the phenyl group is unsubstituted or substituted by one or more substituents independently chosen from halogen atoms, alkyl, trifluoromethyl, hydroxy, alkoxy, methylthio, amino, mono- and dialkylamino, hydroxyalkyl and hydroxycarbonyl groups;
• R3 and R4, which may be the same or different, represent, independently of each other, a group chosen from a hydrogen atom, alkyl, alkenyl and alkynyl groups, wherein the alkyl, alkenyl, and alkynyl groups are unsubstituted or substituted by one or more halogen atoms;
• and
• X represents a single bond, an oxygen atom, or a methylene group;
• , or a pharmaceutically acceptable salt thereof, in any enantiomeric form, or a mixture of any such compounds in any ratio.