Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof

A cosmetic composition useful for body and/or hair hygiene, comprising a thus effective amount of a biaromatic compound having the structural formula (I):

• in which:
• R1 is an alkyl radical having from 1 to 12 carbon atoms, or a radical selected from among those of formulae a)-c):
• b) —(CH2)m—(CO)n—(X)p—(CH2)q—R5 or
• c) an α-amino acid N-protected with an amine-protecting group,
• wherein R5, X, m, n, p and q are as defined below;
• R2 is a radical of formula(a)
• wherein R7 is as defined below;
• R3 is a hydrogen atom, a halogen atom, an alkyl radical having from 1 to 12 carbon atoms, a hydroxyl radical, an alkoxy radical having from 1 to 7 carbon atoms, an aralkoxy radical, an aryloxy radical, a polyether radical, a nitro radical, an amino radical optionally substituted with one or more alkyl radicals having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, a heteroaryl radical or a heterocyclic radical;
• R4 is an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, a heteroaryl radical, a heterocyclic radical, a 9-fluorenylmethyl radical, a radical —(CH2)a—(N—R12)b—(CO)c—R6 or a radical —(CH2)a—(N—R12)b—(CNR15)c—R6, wherein R6, R12, R15, a, b and c are as defined below;
• R5 is a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms, an alkoxy radical having from 1 to 7 carbon atoms, an aralkoxy radical, an aryloxy radical, an aryl radical, an aralkyl radical, a heteroaryl radical, a heterocyclic radical or a group (CO)s(Z)tR6, wherein Z, R6, s and t are as defined below;
• a, b, c, m, n, p, q, s and t have the values 0, 1 or 2;
• X is an oxygen atom, a sulfur atom or NR6, wherein R6 is as defined below;
• Z is an oxygen atom, a nitrogen atom or a sulfur atom;
• R6 and R7, which may be identical or different, are each a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, a heteroaryl radical or a heterocyclic radical;
• R15 is a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, a heteroaryl radical or a heterocyclic radical;
• R10 is a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, a heteroaryl radical or a heterocyclic radical;
• R14 is a halogen atom;
• A is a radical having the following structure:
• —(CH2)z—(N—R12)y—(CO)x-(D)w or —(CH2)z—(N—R12)y—(CS)x—(D)w,
• wherein D, w, x, y, z and R12 are as defined below;
• D is an oxygen atom, a sulfur atom, a radical —NR13 or a CH2 radical;
• wherein w, x, y, z and R13 are as defined below;
• w, x, y and z, which may be identical or different, have the values 0 or 1, with the proviso that the sum x+y+z+w is greater than 2, and when x=0, then y or w=0;
• R12 and R13 are each a hydrogen atom or an alkyl radical having from 1 to 12 carbon atoms, and the optical isomers and salts and mixtures thereof,
• formulated into a cosmetically acceptable support therefor.