Pyrrolopyridine derivative and use thereof
AssigneeTakeda Pharmaceutical Company Limited
InventorsTakahiro Matsumoto, Osamu Kurasawa, Tsuneo Oda, Hiroshi Nagabukuro, Manabu Mochizuki
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AssigneeTakeda Pharmaceutical Company Limited
InventorsTakahiro Matsumoto, Osamu Kurasawa, Tsuneo Oda, Hiroshi Nagabukuro, Manabu Mochizuki
Estimating the term…
A novel pyrrolopyridine derivative which is a compound represented by the formula wherein Ring A represents an optionally substituted pyridine ring; X represents an electron-attracting group; Y represents an optionally substituted divalent C1-6 chain hydrocarbon group; R1 represents an optionally substituted hydrocarbon group; and R2 and R3 each independently represents hydrogen, an optionally substituted hydrocarbon group or an optionally-substituted heterocyclic group, or R2 and R3 may form an optionally substituted ring in cooperation with the adjacent nitrogen atom, or a salt of the compound. The pyrrolopyridine derivative has vanilloid receptor agonist activity and is useful as medicines such as a preventive/therapeutic agent and analgesic for overactive bladder.
A compound represented by the formula
(2E)-3-{3-cyano-4,6-dimethyl-1-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]-1H-pyrrolo[2,3-b]pyridin-2-yl}-N-(3,4-dimethoxyphenyl)prop-2-enamide,
Dependencies are inferred from the claim text.