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US 7,582,622 B2Granted
Steroids having a mixed androgenic and progestagenic profile
AssigneeN.V. Organon
InventorsJaap Van Der Louw, Dirk Leysen, Arij Jan Grootenhuis, Marcel Evert De Gooijer
Life of this patent
Estimating the term…
Abstract
The invention provides 19-nor-D-homosteroids, having a mixed androgenic/progestagenic profile, which are orally active, prevent trabecular bone mineral density (BMD) loss, and which lack liver toxicity, having a structure according to the formula (I) wherein, R1 is O, or NOR, with R being hydrogen, (C1-6)alkyl, or (C1-6)acyl, R2 is methyl or ethyl, and R3 is hydrogen or (C1-15)acyl.
Claims12
A compound of formula I,
- wherein,
- R1 is O, or NOR, with R being hydrogen, (C1-6) alkyl or (C1-6) acyl,
- R2 is methyl or ethyl, and
- R3 is hydrogen or (C1-15) acyl.
1 more element
The compound (7α,17aβ)-17a-hydroxy-7,17a-dimethyl-D-homoestr-4-en-3 -one.
Dependencies are inferred from the claim text.