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US 7,582,603 B2Granted
Method for treating or inhibiting intestinal inflammation
AssigneeUniversity of Maryland, Baltimore
InventorAlessio Fasano
Life of this patent
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Abstract
Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the opening of mammalian tight junctions.
Claims12
A method for treating or inhibiting intestinal inflammation comprising administering to a subject in need of such treatment, a pharmaceutical composition comprising an effective amount of a peptide, the amino acid sequence of the peptide consisting of SEQ ID NO:15.
Dependencies are inferred from the claim text.